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      • Role of VLDL Receptor in the Process of Foam Cell Formation

        Summary: The role of very low density lipoprotein receptor (LVLDR) in the process of foam cell formation was investigated. After the primary cultured mouse peritoneal macrophages were incubated with VLDL, β-VLDL or low density lipoprotein (LDL), respectively for 24 h and 48 h, foam cells formation was identified by oil red O staining and cellular contents of triglyceride (TG) and total cholesterol (TC) were determined. The mRNA levels of LDLR, LDLR related protein (LRP)and VLDLR were detected by semi-quantitative RT-PCR. The results demonstrated that VLDL, βVLDL and LDL could increase the contents of TG and TC in macrophages. Cells treated with VLDL or β-VLDL showed markedly increased expression of VLDLR and decreased expression of LDLR, whereas LRP was up-regulated slightly. For identifying the effect of VLDL receptor on cellular lipid accumulation, Idl-A7-VR cells, which expresses VLDLR and trace amount of LRP without functional LDLR, was used to incubate with lipoproteins for further examination. The results elucidated that the uptake of triglyceride-rich lipoprotein mediated by VLDLR plays an important role in accumulation of lipid and the formation of foam cells....

        2020-11-10 09:33:08瀏覽:20 verylowdensitylipoproteinreceptortriglyceride-richexpression

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      • Water-conserving Potential for Agriculture in the Tarim Basin

        To satisfy the water demand for Tarim Basin's economic development in the year 2000, about 33.4×108 m3 water needs to be further tapped. Acco rding t o the analysis of the current status of water utilization, it is pointed out th at, to achieve such economic objectives, the policy of emphasizing both water ex ploitation and water conservation with the preference given to conservation meas ures must be followed. For this end, the potentials of exploring new additional sources and strengthening water conservation have been well analyzed, along with the calculation and tech-economic-assessment of some related parameters like the canal transmission efficiency in water delivery systems and the water irrigation effi ciency in the field. The results indicate the potentials of water resource expan sion and conservation are 34×108 m3 and 57×108 m3, respectively. Bas ed on such rese arch outputs, a water conservation program has been developed for the Tarim Basi n, to provide important references and policy recommendations for the decision- makers in Xinjiang agricultural department to implement water utilization measur es....

        2020-07-08 08:49:41瀏覽:21 waterconservationpotentialsourceexpansiondeliverysystem

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      [!--page.stats--] 被公玩弄的年轻人妻

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